Ehemalige Forschungsgruppe Große
Publikationen
- DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding.
Szambowska A, Tessmer I, Kursula P, Usskilat C, Prus P, Pospiech H, Grosse F
Nucleic Acids Res 2014, 42(4), 2308-19 - Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.
Villani G, Shevelev I, Orlando E, Pospiech H, Syvaoja JE, Markkanen E, Hubscher U, Le Gac NT
PLoS One 2014, 9(4), e93908 - Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer.
Li H, Hassona MD, Lack NA, Axerio-Cilies P, Leblanc E, Kanaan N, Frewin K, Singh K, Adomat H, Böhm KJ, Prinz H, Guns ET, Rennie PS, Cherkasov A
Mol Cancer Ther 2013, 12(11), 2425-35 - RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
Mills JR, Malina A, Lee T, Di Paola D, Larsson O, Miething C, Grosse F, Tang H, Zannis-Hadjopoulos M, Lowe SW, Pelletier J
Blood 2013, 121(17), 3402-12 - Heterozygous mutations in PALB2 cause DNA replication and damage response defects.
Nikkilä J, Parplys AC, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech* H, Winqvist* R
Nat Commun 2013, 4, 2578 * equal contribution
