Publikationen

2016

• Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis.
  Coburger I, Schaub Y, Roeser D, Hardes K, Maeder P, Klee N, Steinmetzer T, Imhof D, Diederich WE, Than ME
  Microbiologyopen 2016, 5(4), 637-46
  
• The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
  Dahms SO, Creemers JWM, Schaub Y, Bourenkov GP, Zögg T, Brandstetter H, Than ME
  Sci Rep 2016, 6, 34303.doi:10.1038/srep303
  
• Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
  Dahms* SO, Arciniega* M, Steinmetzer T, Huber** R, Than** ME
  Proc Natl Acad Sci U S A 2016, 113(40), 11196-201 * equal contribution, ** co-corresponding authors
  

2015

• Struktur und Funktion des Amyloid-Vorläuferproteins (APP) und seiner Interaktionspartner
  Coburger I
  Dissertation 2015, Jena, Germany
  
• Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
  Dahms SO, Mayer MC, Roeser D, Multhaup G, Than ME
  Acta Crystallogr D Biol Crystallogr 2015, 71(Pt 3), 494-504