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Publikationen Projekt Biochemie

2019

  • BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells.
    Bose M, Sachsenweger J, Laurila N, Parplys AC, Willmann J, Jungwirth J, Groth M, Rapakko K, Nieminen P, Friedl TWP, Heiserich L, Meyer F, Tuppurainen H, Peltoketo H, Nevanlinna H, Pylkäs K, Borgmann K, Wiesmüller L, Winqvist** R, Pospiech** H
    Hum Mol Genet 2019, 28(24), 4148-60 ** co-corresponding authors
  • Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus.
    Siebenwirth C, Greubel C, Drexler GA, Reindl J, Walsh DWM, Schwarz B, Sammer M, Baur I, Pospiech H, Schmid TE, Dollinger G, Friedl AA
    J Cell Sci 2019, 132(19), jcs232181

2018

  • The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S Phase.
    Sokka* M, Koalick* D, Hemmerich P, Syväoja JE, Pospiech H
    Int J Mol Sci 2018, 19(8) * equal contribution

2017

  • Toxic effects of zinc ions on kinesin - Potential molecular cause of impaired intracellular transport.
    Böhm KJ
    Toxicol Lett 2017, 268, 58-62
  • Regulation und Deregulation eukaryotischer DNA-Replikation
    Keller-Koalick D
    Dissertation 2017, Jena, Germany
  • N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization.
    Prinz H, Ridder AK, Vogel K, Böhm KJ, Ivanov I, Ghasemi J, Aghaee E, Müller K:
    J Med Chem 2017, 60(2), 749-66
  • Local responses of S phase cells post irradiation damage
    Smith SJ
    Dissertation 2017, Jena, Germany
  • Cdc45-induced loading of human RPA onto single-stranded DNA.
    Szambowska A, Tessmer I, Prus P, Schlott B, Pospiech H, Grosse F
    Nucleic Acids Res 2017, 45(6), 3217-30

2016

  • S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.
    Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech** H, Grosse F, Melle** C
    Cell Cycle 2016, 15(20), 2766-79 ** co-corresponding authors
  • DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.
    Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L
    Proc Natl Acad Sci U S A 2016, 113(30), E4311-9