Forschungsgruppe von Eyss

Publikationen am FLI

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, Eifert T, Hsu CJ, Perner F, Zhang Q, Wenge DV, Hansen FM, Kirkpatrick JM, Jyotsana N, Lane SW, von Eyss B, Deshpande AJ, Kühn MWM, Schwaller J, Cammann C, Seifert U, Ebstein F, Krüger E, Hochhaus A, Heuser M, Ori A, Mann M, Armstrong SA, Heidel FH
Mol Cancer 2023, 22(1), 196

Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity.
Kim* KM, Mura-Meszaros* A, Tollot* M, Krishnan MS, Gründl M, Neubert L, Groth M, Rodriguez-Fraticelli A, Svendsen AF, Campaner S, Andreas N, Kamradt T, Hoffmann S, Camargo FD, Heidel FH, Bystrykh LV, de Haan G, von Eyss B
Nat Commun 2022, 13(1), 5187 * equal contribution
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss Bv, Bonifer C, Heidel F
Blood 2022, 139(7), 1080-97

Genome-wide functional CRISPR-Cas9 screening reveals key roles of GOLT1A and GOLT1B in the FLI-06-mediated secretion block
Cramer P
Dissertation 2021, Jena, Germany
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W
Proc Natl Acad Sci U S A 2021, 118(22)
A comprehensive transcriptome signature of murine hematopoietic stem cell aging.
Svendsen AF, Yang D, Kim KM, Lazare SS, Skinder N, Zwart E, Mura-Meszaros A, Ausema A, Eyss Bv, de Haan G, Bystrykh LV
Blood 2021, 138(6), 439-51

Control mechanisms of YAP activity
Elster D
Dissertation 2020, Jena, Germany
Hippo Signaling in Regeneration and Aging.
Elster D, von Eyss B
Mech Ageing Dev 2020, 189, 111280
The role of Hippo signaling in hematopoietic stem cell aging
Mura-Mészáros A
Dissertation 2020, Jena, Germany
Der Hippo-Signalweg in der Regeneration und im Krebs
Tollot M, Cindric Vranesic A, von Eyss B
BIOspektrum 2020, 26, 154–157