Publikationen

2025

• The evolving landscape of epigenetic target molecules and therapies in myeloid cancers: focus on acute myeloid leukemia and myeloproliferative neoplasms.
  Kühn MWM, Pemmaraju N, Heidel FH
  Leukemia 2025 (epub ahead of print)
  
• Pathogenesis and management of high molecular risk myeloproliferative neoplasms.
  Ling VY, Heidel FH, Bywater MJ
  Haematologica 2025, 110(4), 863-76
  
• Oncogenic FLT3 internal tandem duplications (ITD) and CD45/PTPRC control osteoclast functions and bone microarchitecture.
  Lossius-Cott C, Annoh A, Bens M, Nietzsche S, Hoffmann B, Figge MT, Rauner M, Hofbauer LC, Müller JP
  JBMR Plus 2025, 9(3), ziae173
  
• Lonafarnib Partially Reverses Cardiac Senescence in Human and Mouse Progeria Models via Autophagy Activation
  M.Monteiro L, R.Pitrez P, Correia-Santos S, Dark N, Santinha D, Aveleira C, Townsend M, Taylor J, Nissan X, Sardão V, Cortes L, Mitter R, Marino A, Sousa-Soares C, Ribeiro R, C.Smith J, Logarinho E, Ori A, S.Bernardo A, Ferreira L
  bioRxiv 2025, https://doi.org/10.1101/2025.06.
  
• Aging and diet alter the protein ubiquitylation landscape in the mouse brain.
  Marino* A, Di Fraia* D, Panfilova D, Sahu AK, Minetti A, Omrani O, Cirri E, Ori A
  Nat Commun 2025, 16(1), 5266 * equal contribution
  
• DNA damage response regulator ATR licenses PINK1-mediated mitophagy.
  Marx* C, Qing* X, Gong* Y, Kirkpatrick J, Siniuk K, Beznoussenko GV, Kidiyoor GR, Kirtay M, Buder K, Koch P, Westermann M, Bruhn C, Brown EJ, Xu X, Foiani M, Wang ZQ
  Nucleic Acids Res 2025, 53(5), gkaf178 * equal contribution
  
• Infection and herbicide exposure implicate c-Abl kinase in α-Synuclein Ser129 phosphorylation
  Marzieh E, Zeyang S, Alvaro QO, Gesa R, Mahdi R, David H, Saskia FE, Thomas FM
  bioRxiv 2025, https://doi.org/10.1101/2025.01.
  
• Analysis of different strains of the turquoise killifish identify transcriptomic signatures associated with heritable lifespan differences.
  Mazzetto M, Reichwald K, Koch P, Groth M, Cellerino A
  J Gerontol A Biol Sci Med Sci 2025 (epub ahead of print)
  
• Prognostic impact of clonal representation of myelodysplasia-related gene mutations in acute myeloid leukemia.
  Mecklenbrauck R, Borchert N, Gabdoulline R, Poll P, Funke C, Brandes M, Dallmann LK, Fiedler W, Krauter J, Trummer A, Hertenstein B, Müller M, Lübbert M, Schwalenberg M, Voss A, Di Donato N, Bergmann A, Gaidzik V, Döhner K, Döhner H, Ganser A, Heidel FH, Thol FR, Heuser M
  Leukemia 2025, 39(7), 1773-7
  
• diffONT: predicting methylation-specific PCR biomarkers based on nanopore sequencing data for clinical application
  Meyer** D, Barth E, Wiehle L, Marz** M
  bioRxiv 2025, https://doi.org/10.1101/2025.02. ** co-corresponding authors