Publications

2010

• The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variability.
  Qiu H, Mathäs M, Nestler S, Bengel C, Nem D, Gödtel-Armbrust U, Lang T, Taudien S, Burk O, Wojnowski L
  Pharmacogenet Genomics 2010, 20(3), 167-78
  
• Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients.
  Radeva MY, Jahns F, Wilhelm A, Glei M, Settmacher U, Greulich KO, Mothes H
  BMC Cancer 2010, 10, 588
  
• Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
  Rauch* A, Seitz* S, Baschant* U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP
  Cell Metab 2010, 11(6), 517-31 * equal contribution
  
• Potential negative impacts and low effectiveness in the use of African annual killifish in the biocontrol of aquatic mosquito larvae in temporary water bodies.
  Reichard M, Watters BR, Wildekamp RH, Sonnenberg R, Nagy B, Polacik M, Valdesalici S, Cellerino A, Cooper BJ, Hengstler H, Rosenstock J, Sainthouse I
  Parasit Vectors 2010, 3, 89
  
• Cellular and molecular dissection of the Nbs1 Role in T cell development using mice model
  Saidi A
  Dissertation 2010, Jena, Germany
  
• Dual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.
  Saidi* A, Li* T, Weih F, Concannon P, Wang ZQ
  Mol Cell Biol 2010, 30(23), 5572-81 * equal contribution
  
• Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.
  Santhiya ST, Kumar GS, Sudhakar P, Gupta N, Klopp N, Illig T, Söker T, Groth M, Platzer M, Gopinath PM, Graw J
  Mol Vis 2010, 16, 1837-47
  
• A subtle alternative splicing event of the Na(V)1.8 voltage-gated sodium channel is conserved in human, rat, and mouse.
  Schirmeyer J, Szafranski K, Leipold E, Mawrin C, Platzer M, Heinemann SH
  J Mol Neurosci 2010, 41(2), 310-4
  
• Cross talk between stimulated NF-kappaB and the tumor suppressor p53.
  Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, Wieczorek M, Wagner T, Reichardt S, von Werder A, Schmid RM, Weih F, Heinzel T, Saur D, Krämer OH
  Oncogene 2010, 29(19), 2795-806
  
• Merlin inhibits neurite outgrowth in the CNS.
  Schulz A, Geissler KJ, Kumar S, Leichsenring G, Morrison* H, Baader* SL
  J Neurosci 2010, 30(30), 10177-86 * equal contribution