Waskow Research Group
Publications at FLI
2024
- Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunity.
Geiselhöringer AL, Kolland D, Patt AJ, Hammann L, Köhler A, Kreft L, Wichmann N, Hils M, Ruedl C, Riemann M, Biedermann T, Anz D, Diefenbach A, Voehringer D, Schmidt-Weber CB, Straub T, Pasztoi M, Ohnmacht C
Nat Commun 2024, 15(1), 9143 - RelB and C/EBPα critically regulate the development of Peyer's patch mononuclear phagocytes.
Kanaya T, Jinnohara T, Sakakibara S, Tachibana N, Sasaki T, Kato T, Riemann M, Jin J, Shiroguchi K, Kawakami E, Ohno H
MUCOSAL IMMUNOL 2024 (epub ahead of print) - CRISPR/Cas9-Mediated Modification of PTP Expression.
Lossius C, Kresinsky A, Quiet L, Müller JP
Methods Mol Biol 2024, 2743, 43 - Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia.
Weinberger T, Denise M, Joppich M, Fischer M, Garcia Rodriguez C, Kumaraswami K, Wimmler V, Ablinger S, Räuber S, Fang J, Liu L, Liu WH, Winterhalter J, Lichti J, Thomas L, Esfandyari D, Percin G, Matin S, Hidalgo A, Waskow C, Engelhardt S, Todica A, Zimmer R, Pridans C, Gomez Perdiguero E, Schulz C
Elife 2024, 12, RP89377
2023
- Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Foßelteder J, Pabst G, Sconocchia T, Schlacher A, Auinger L, Kashofer K, Beham-Schmid C, Trajanoski S, Waskow C, Schöll W, Sill H, Zebisch A, Wölfler A, Thomas D, Reinisch A
Leukemia 2023, 37(4), 843-53 - T Cells Expressing a Modified FcγRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors.
Rasoulouniriana D, Santana-Magal N, Gutwillig A, Farhat-Younis L, Tal L, Amar S, Milyavsky M, Muddineni SSNA, Solomon N, Shpilt H, Dotan S, Pilpel N, Waskow C, Feinmesser M, Rider P, Carmi Y
CANCER IMMUNOL RES 2023, 11(6), 792
2022
- Impaired formation of neutrophil extracellular traps (NETs) in patients with myelodysplastic syndrome.
Brings C, Fröbel J, Cadeddu RP, Germing U, Haas R, Gattermann N
BLOOD ADV 2022, 6(1), 129-37 - Disrupting PTPRJ transmembrane-mediated oligomerization counteracts oncogenic receptor tyrosine kinase FLT3 ITD.
Schwarz M, Rizzo S, Paz WE, Kresinsky A, Thévenin D, Müller JP
Front Oncol 2022, 12, 1017947
2021
- BCL3 couples cancer stem cell enrichment with pancreatic cancer molecular subtypes.
Ai J, Wörmann SM, Görgülü K, Vallespinos M, Zagorac S, Alcala S, Wu N, Kabacaoglu D, Berninger A, Navarro D, Kaya-Aksoy E, Ruess DA, Ciecielski KJ, Kowalska M, Demir EI, Ceyhan GO, Heid I, Braren R, Riemann M, Schreiner S, Hofmann S, Kutschke M, Jastroch M, Slotta-Huspenina J, Muckenhuber A, Schlitter AM, Schmid RM, Steiger K, Diakopoulos KN, Lesina M, Sainz B, Algül H
Gastroenterology 2021, 161(1), 318-32 - Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7.
Coppin* E, Sundarasetty* BS, Rahmig S, Blume J, Verheyden NA, Bahlmann F, Ravens S, Schubert U, Schmid J, Ludwig S, Geissler K, Guntinas-Lichius O, von Kaisenberg C, Groten T, Platz A, Naumann R, Ludwig B, Prinz I, Waskow** C, Krueger** A
Leukemia 2021, 35(12), 3561-7 * equal contribution, ** co-senior authors
Selected Publications
- SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt K, Kranz A, Fohgrub J, Jolly A, Bledau AS, Di Virgilio M, Lesche M, Dahl A, Höfer T, Stewart AF, Waskow C
Blood 2018, 131(12), 1311-24 - Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells.
Schreck C, Istvánffy R, Ziegenhain C, Sippenauer T, Ruf F, Henkel L, Gärtner F, Vieth B, Florian MC, Mende N, Taubenberger A, Prendergast Á, Wagner A, Pagel C, Grziwok S, Götze KS, Guck J, Dean DC, Massberg S, Essers M, Waskow C, Geiger H, Schiemann M, Peschel C, Enard W, Oostendorp RAJ
J Exp Med 2017, 214(1), 165-81 - Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice.
Rahmig S, Kronstein-Wiedemann R, Fohgrub J, Kronstein N, Nevmerzhitskaya A, Bornhäuser M, Gassmann M, Platz A, Ordemann R, Tonn T, Waskow C
Stem Cell Reports 2016, 7(4), 591-601 - The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis.
Schoedel KB, Morcos MNF, Zerjatke T, Roeder I, Grinenko T, Voehringer D, Göthert JR, Waskow C, Roers A, Gerbaulet A
Blood 2016, 128(19), 2285-96 - Space constraints govern fate of hematopoietic stem and progenitor cells in vitro.
Müller E, Grinenko T, Pompe T, Waskow C, Werner C
Biomaterials 2015, 53, 709-15 - CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo.
Mende N, Kuchen EE, Lesche M, Grinenko T, Kokkaliaris KD, Hanenberg H, Lindemann D, Dahl A, Platz A, Höfer T, Calegari F, Waskow C
J Exp Med 2015, 212(8), 1171-83 - Kit regulates HSC engraftment across the human-mouse species barrier.
Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnjevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C
Cell Stem Cell 2014, 15(2), 227-38 - Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells.
Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun KN, Alexopoulou D, Lakshmanaperumal N, Henry I, Dahl A, Waskow C
J Exp Med 2014, 211(2), 209-15 - Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments.
Prewitz MC, Seib FP, von Bonin M, Friedrichs J, Stißel A, Niehage C, Müller K, Anastassiadis K, Waskow C, Hoflack B, Bornhäuser M, Werner C
Nat Methods 2013, 10(8), 788-94 - CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells.
Arndt K, Grinenko T, Mende N, Reichert D, Portz M, Ripich T, Carmeliet P, Corbeil D, Waskow C
Proc Natl Acad Sci U S A 2013, 110(14), 5582-7