Publications

2025

• Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity.
  Hupa-Breier KL, Schenk H, Campos-Murguia A, Wellhöner F, Heidrich B, Dywicki J, Hartleben B, Böker C, Mall J, Terkamp C, Wilkens L, Becker F, Rudolph KL, Manns MP, Mederacke YS, Marhenke S, Redeker H, Lieber M, Iordanidis K, Taubert R, Wedemeyer H, Noyan F, Hardtke-Wolenski M, Jaeckel E
  Mol Metab 2025 (epub ahead of print)
  
• Infection and herbicide exposure implicate c-Abl kinase in α-Synuclein Ser129 phosphorylation
  Marzieh E, Zeyang S, Alvaro QO, Gesa R, Mahdi R, David H, Saskia FE, Thomas FM
  bioRxiv 2025, https://doi.org/10.1101/2025.01.
  

2024

• Dietary restriction interventions: lifespan benefits need resilience and are limited by immune compromise and genetics.
  Chen Y, Malik A, Rudolph KL
  Signal Transduct Target Ther 2024, 9(1), 335
  
• The oncogenic lncRNA MIR503HG suppresses cellular senescence counteracting supraphysiological androgen treatment in prostate cancer.
  Kallenbach J, Rasa M, Heidari Horestani M, Atri Roozbahani G, Schindler K, Baniahmad A
  J Exp Clin Cancer Res 2024, 43(1), 321
  
• Optimizing Biocompatibility and Gene Delivery with DMAEA and DMAEAm: A Niacin-Derived Copolymer Approach.
  Mapfumo PP, Reichel LS, André T, Hoeppener S, Rudolph LK, Traeger A
  Biomacromolecules 2024 (epub ahead of print)
  
• Vitamin B3 Containing Polymers for Nanodelivery.
  Mapfumo PP, Solomun JI, Becker F, Moek E, Leiske MN, Rudolph LK, Brendel JC, Traeger A
  Macromol Biosci 2024, e2400002
  

2023

• Evolution, mechanism and limits of dietary restriction induced health benefits and longevity.
  Becker F, Behrends MM, Rudolph KL
  Redox Biol 2023, 63, 102725
  
• Genetic separation of chronic myeloid leukemia stem cells from normal hematopoietic stem cells at single-cell resolution.
  Chen Y, Möbius S, Riege K, Hoffmann S, Hochhaus A, Ernst* T, Rudolph* KL
  Leukemia 2023, 37(7), 1561-6 * equal contribution
  
• A YIPF5-GOT1A/B complex directs a transcription-independent function of ATF6 in ER export
  Cramer P, Yonemura Y, Behrendt L, Marszalek A, Sannai M, Durso W, Günes C, Szafranski K, Nakamura N, Nasrashvili T, Mayer J, von Eyss** B, Kaether** C
  bioRxiv 2023, 10.1101/2023.12.12.569033 ** co-corresponding authors
  
• Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium.
  Garside GB, Sandoval M, Beronja** S, Rudolph** KL
  BMC Biol 2023, 21(1), 6 ** co-corresponding authors