Publications

2024

• Optimizing Biocompatibility and Gene Delivery with DMAEA and DMAEAm: A Niacin-Derived Copolymer Approach.
  Mapfumo PP, Reichel LS, André T, Hoeppener S, Rudolph LK, Traeger A
  Biomacromolecules 2024 (epub ahead of print)
  
• Vitamin B3 Containing Polymers for Nanodelivery.
  Mapfumo PP, Solomun JI, Becker F, Moek E, Leiske MN, Rudolph LK, Brendel JC, Traeger A
  Macromol Biosci 2024, e2400002
  

2023

• Evolution, mechanism and limits of dietary restriction induced health benefits and longevity.
  Becker F, Behrends MM, Rudolph KL
  Redox Biol 2023, 63, 102725
  
• Genetic separation of chronic myeloid leukemia stem cells from normal hematopoietic stem cells at single-cell resolution.
  Chen Y, Möbius S, Riege K, Hoffmann S, Hochhaus A, Ernst* T, Rudolph* KL
  Leukemia 2023, 37(7), 1561-6 * equal contribution
  
• A YIPF5-GOT1A/B complex directs a transcription-independent function of ATF6 in ER export
  Cramer P, Yonemura Y, Behrendt L, Marszalek A, Sannai M, Durso W, Günes C, Szafranski K, Nakamura N, Nasrashvili T, Mayer J, von Eyss** B, Kaether** C
  bioRxiv 2023, 10.1101/2023.12.12.569033 ** co-corresponding authors
  
• Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium.
  Garside GB, Sandoval M, Beronja** S, Rudolph** KL
  BMC Biol 2023, 21(1), 6 ** co-corresponding authors
  
• IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
  Omrani* O, Krepelova* A, Rasa SMM, Sirvinskas D, Lu J, Annunziata F, Garside G, Bajwa S, Reinhardt S, Adam L, Käppel S, Ducano N, Donna D, Ori A, Oliviero S, Rudolph KL, Neri F
  Nat Commun 2023, 14(1), 6109 * equal contribution
  
• Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging.
  Rommelfanger* MK, Behrends* M, Chen Y, Martinez J, Bens M, Xiong L, Rudolph** KL, MacLean** AL
  bioRxiv 2023, 10.1101/2023.04.18.537360 * equal contribution, ** co-corresponding authors
  

2022

• Vitamin A metabolism in niche cells activates retinoic acid signaling and impairs stem cell function and skeletal muscle maintenance in aging mice
  Becker F
  Dissertation 2022, Jena
  
• Meeting Report: Aging Research and Drug Discovery
  Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald Collin Y, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Borch Jensen M, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M
  Aging (Albany NY) 2022, 14(2), 530–543