2025
- Analysis of different strains of the turquoise killifish identify transcriptomic signatures associated with heritable lifespan differences.
Mazzetto M, Reichwald K, Koch P, Groth M, Cellerino A
J Gerontol A Biol Sci Med Sci 2025 (epub ahead of print) - The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization.
Richter A, Mörl H, Thielemann M, Kleemann M, Geißen R, Schwarz R, Albertz C, Koch P, Petzold A, Kroll T, Groth M, Hartmann N, Herpin A, Englert C
Nat Commun 2025, 16(1), 540 - Gene regulation by convergent promoters.
Wiechens E, Vigliotti* F, Siniuk* K, Schwarz R, Schwab K, Riege K, van Bömmel A, Görlich I, Bens M, Sahm A, Groth M, Sammons MA, Loewer A, Hoffmann S, Fischer M
Nat Genet 2025 (epub ahead of print) * equal contribution
2024
- INHBA is enriched in HPV-negative oropharyngeal squamous cell carcinoma and promotes cancer progression.
Abou Kors T, Hofmann L, Betzler A, Payer K, Bens M, Truong J, von Witzleben A, Thomas J, Kraus JM, Kalaajieh R, Huber D, Ezić J, Benckendorff J, Greve J, Schuler PJ, Ottensmeier CH, Kestler HA, Hoffmann TK, Theodoraki MN, Brunner C, Laban S
Cancer Res Commun 2024 (epub ahead of print) - Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal squamous cell carcinoma, with a focus on cancer-testis antigens.
Abou Kors T, Meier M, Mühlenbruch L, Betzler AC, Oliveri F, Bens M, Thomas J, Kraus JM, Doescher J, von Witzleben A, Hofmann L, Ezic J, Huber D, Benckendorff J, Barth TFE, Greve J, Schuler PJ, Brunner C, Blackburn JM, Hoffmann TK, Ottensmeier C, Kestler HA, Rammensee HG, Walz JS, Laban S
Front Immunol 2024, 15, 1408173 - Metabolic modeling reveals the aging-associated decline of host-microbiome metabolic interactions in mice
Best L, Dost T, Esser D, Flor S, Haase M, Kadibalban AS, Marinos G, Walker A, Zimmermann J, Simon R, Schmidt S, Taubenheim J, Künzel S, Häsler R, Groth M, Waschina S, W.Witte O, Schmitt-Kopplin P, F.Baines J, Frahm C, Kaleta C
bioRxiv 2024, https://doi.org/10.1101/2024.03. - Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.
Burkhalter MD, Stiff T, Maerz LD, Casar Tena T, Wiese H, Gerhards J, Sailer SA, Vu LAT, Duong Phu M, Donow C, Alupei M, Iben S, Groth M, Wiese S, Church JA, Jeggo PA, Philipp M
Cell Death Dis 2024, 15(9), 660 - The Aging Synapse: An Integrated Proteomic And Transcriptomic Analysis
Caterino* C, Ugolini* M, Durso W, Jevdokimenko K, Groth M, Riege K, Görlach M, Fornasiero E, Ori A, Hoffmann S, Cellerino A
bioRxiv 2024, https://doi.org/10.1101/2024.12. * equal contribution - Amyloid beta precursor protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
E.M.de Bakker D, Mihaljević M, Gharat K, Richter Y, Bagnoli S, van Bebber F, Adam L, Shamim-Schulze F, Ohlenschläger O, Bens M, Cirri E, Antebi A, Matić I, Schneider A, Schmid B, Cellerino A, Kirstein J, Riccardo Valenzano D
bioRxiv 2024, https://doi.org/10.1101/2024.10. - Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality.
Henze H, Hüttner SS, Koch P, Schüler SC, Groth M, von Eyss B, von Maltzahn J
NPJ Regen Med 2024, 9(1), 10