Project Biochemistry (until 2023)
Publications
2024
- HROB Is Implicated in DNA Replication.
Kutz J, Schmietendorf H, Rahman SA, Opel F, Pospiech H
Genes (Basel) 2024, 15(12) - Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase.
Pallasaho S, Gondane A, Kutz J, Liang J, Yalala S, Duveau DY, Pospiech H, Thomas CJ, Loda M, Itkonen HM
Glycobiology 2024 (epub ahead of print) - Role of UFMylation and Ubiquitylation of MCM7 during DNA replication
Yuan S
Dissertation 2024, Jena, Germany
2023
- Targeting cellular pathways in hyper- and ultramutated cancer cells with exonuclease-defective DNA polymerase epsilon
Borges G
Dissertation 2023, Jena, Germany - ABRAXAS1 orchestrates BRCA1 activities to counter genome destabilizing repair pathways-lessons from breast cancer patients.
Sachsenweger J, Jansche R, Merk T, Heitmeir B, Deniz M, Faust U, Roggia C, Tzschach A, Schroeder C, Riess A, Pospiech H, Peltoketo H, Pylkäs K, Winqvist R, Wiesmüller L
Cell Death Dis 2023, 14(5), 328