Publikationen

2023

• Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.
  Izadi M, Wolf D, Seemann E, Ori A, Schwintzer L, Steiniger F, Kessels MM, Qualmann B
  J Cell Biol 2023, 222(8)
  
• Remodeling of the protein ubiquitylation landscape in the aging vertebrate brain
  Marino* A, Di Fraia* D, Panfilova D, Kumar Sahu A, Ori A
  bioRxiv 2023, 10.1101/2023.12.02.569713 * equal contribution
  
• IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
  Omrani* O, Krepelova* A, Rasa SMM, Sirvinskas D, Lu J, Annunziata F, Garside G, Bajwa S, Reinhardt S, Adam L, Käppel S, Ducano N, Donna D, Ori A, Oliviero S, Rudolph KL, Neri F
  Nat Commun 2023, 14(1), 6109 * equal contribution
  
• Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
  Schädel P, Czapka A, Gebert N, Jacobsen ID, Ori** A, Werz** O
  Aging Cell 2023, 22(7), e13856 ** co-corresponding authors
  
• Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
  Schädel P, Wichmann-Costaganna M, Czapka A, Gebert N, Ori A, Werz O
  Nutrients 2023, 15(16), 3660
  
• Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
  Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, Eifert T, Hsu CJ, Perner F, Zhang Q, Wenge DV, Hansen FM, Kirkpatrick JM, Jyotsana N, Lane SW, von Eyss B, Deshpande AJ, Kühn MWM, Schwaller J, Cammann C, Seifert U, Ebstein F, Krüger E, Hochhaus A, Heuser M, Ori A, Mann M, Armstrong SA, Heidel FH
  Mol Cancer 2023, 22(1), 196
  

2022

• Investigating the proteasome interaction network using proximity ligation coupled to mass spectrometry
  Bartolome A
  Dissertation 2022, Jena, Germany
  
• Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
  Ciuffa R, Uliana F, Mannion J, Mehnert M, Tenev T, Marulli C, Satanowski A, Keller LML, Rodilla Ramírez PN, Ori A, Gstaiger M, Meier P, Aebersold R
  Proc Natl Acad Sci U S A 2022, 119(40), e2117175119
  
• Conserved exchange of paralog proteins during neuronal differentiation.
  Di Fraia D, Anitei M, Mackmull MT, Parca L, Behrendt L, Andres-Pons A, Gilmour D, Helmer Citterich M, Kaether C, Beck M, Ori A
  Life Sci Alliance 2022, 5(6)
  
• Metabolic determination of cell fate through selective inheritance of mitochondria.
  Döhla J, Kuuluvainen E, Gebert N, Amaral A, Englund JI, Gopalakrishnan S, Konovalova S, Nieminen AI, Salminen ES, Torregrosa Muñumer R, Ahlqvist K, Yang Y, Bui H, Otonkoski T, Käkelä R, Hietakangas V, Tyynismaa H, Ori A, Katajisto P
  Nat Cell Biol 2022, 24(2), 148-54