Publikationen

2015

• Mutants of Metal Binding Site M1 in APP E2 Show Metal Specific Differences in Binding of Heparin but Not of sorLA.
  Dienemann C, Coburger I, Mehmedbasic A, Andersen OM, Than ME
  Biochemistry 2015, 54(15), 2490-9
  
• Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors.
  Fittler H, Depp A, Avrutina O, Dahms SO, Than ME, Empting M, Kolmar H
  Chembiochem 2015, 16(17), 2441-4
  
• Novel Furin Inhibitors with Potent Anti-infectious Activity.
  Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T
  ChemMedChem 2015, 10(7), 1218-31
  
• The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain.
  Hoefgen S, Dahms SO, Oertwig K, Than ME
  J Mol Biol 2015, 427(2), 433-42
  
• Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
  Lu Y, Hardes K, Dahms SO, Böttcher-Friebertshäuser E, Steinmetzer T, Than ME, Klenk HD, Garten W
  Antiviral Res 2015, 120, 89-100