Publikationen

2022

• Glycation Alters the Fatty Acid Binding Capacity of Human Serum Albumin.
  Henning C, Stübner C, Arabi SH, Reichenwallner J, Hinderberger D, Fiedler R, Girndt M, Di Sanzo S, Ori A, Glomb MA
  J Agric Food Chem 2022, 70(9), 3033-46
  
• Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.
  Kluever V, Russo B, Mandad S, Kumar NH, Alevra M, Ori A, Rizzoli SO, Urlaub H, Schneider A, Fornasiero EF
  Sci Adv 2022, 8(20), eabn4437
  
• Multifaceted Microcephaly-Related Gene MCPH1
  Kristofova M, Ori A, Wang ZQ
  Cells 2022, 11(2), 275
  
• CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
  Laqtom NN, Dong W, Medoh UN, Cangelosi AL, Dharamdasani V, Chan SH, Kunchok T, Lewis CA, Heinze I, Tang R, Grimm C, Dang Do AN, Porter FD, Ori A, Sabatini DM, Abu-Remaileh M
  Nature 2022, 609(7929), 1005-11
  
• Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.
  Rasa* SMM, Annunziata* F, Krepelova A, Nunna S, Omrani O, Gebert N, Adam L, Käppel S, Höhn S, Donati G, Jurkowski TP, Rudolph KL, Ori A, Neri F
  Cell Rep 2022, 39(13), 111017 * equal contribution
  
• PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
  Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss Bv, Bonifer C, Heidel F
  Blood 2022, 139(7), 1080-97
  
• Single-cell atlas of the aging mouse colon.
  Širvinskas D, Omrani O, Lu J, Rasa M, Krepelova A, Adam L, Kaeppel S, Sommer F, Neri F
  iScience 2022, 25(5), 104202
  

2021

• Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice.
  Dabaghi M, Rasa SMM, Cirri E, Ori A, Neri F, Quaas R, Hilger I
  Pharmaceutics 2021, 13(10)
  
• Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis.
  Deb S, Felix DA, Koch P, Deb MK, Szafranski K, Buder K, Sannai M, Groth M, Kirkpatrick J, Pietsch S, Gollowitzer A, Groß A, Riemenschneider P, Koeberle A, González-Estévez** C, Rudolph** KL
  EMBO Rep 2021, 22(1), e49328 ** co-corresponding authors
  
• Mapping sites of carboxymethyllysine modification on proteins reveals its consequences for proteostasis and cell proliferation
  Di Sanzo S
  Dissertation 2021, Jena, Germany