Forschungsgruppe Rudolph

Publikationen

2022

  • Identification of dynamic driver sets controlling phenotypical landscapes.
    Werle SD, Ikonomi N, Schwab JD, Kraus JM, Weidner FM, Rudolph KL, Pfister AS, Schuler R, Kühl M, Kestler HA
    Comput Struct Biotechnol J 2022, 20, 1603-17
  • S-nitrosoglutathione reductase (GSNOR) deficiency impairs hematopoietic stem cell proteostasis
    Yi W
    Dissertation 2022, Jena, Germany

2021

  • Targeting enzyme aging.
    Becker F, Rudolph KL
    Science 2021, 371(6528), 462-3
  • Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.
    Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL
    J Clin Invest 2021, 131(1) Corrigendum for J Clin Invest. 2012;122(6):2283–2288
  • Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cells.
    Chen Y, Rudolph KL
    Haematologica 2021, 106(6), 1516-8
  • Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis.
    Deb S, Felix DA, Koch P, Deb MK, Szafranski K, Buder K, Sannai M, Groth M, Kirkpatrick J, Pietsch S, Gollowitzer A, Groß A, Riemenschneider P, Koeberle A, González-Estévez** C, Rudolph** KL
    EMBO Rep 2021, 22(1), e49328 ** co-corresponding authors
  • Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response.
    Gutiérrez-Gutiérrez* Ó, Felix* DA, Salvetti A, Amro EM, Thems A, Pietsch S, Koeberle A, Rudolph KL, González-Estévez C
    EMBO Rep 2021, 22(8), e52905 * equal contribution
  • Deletion of H2AX aggravates telomere dysfunction induced DNA damage and atrophy of the intestinal epithelium
    Omrani O
    Dissertation 2021, Jena, Germany
  • DNA-methylation aging at single-cell level
    Rudolph KL
    Nature Aging 2021, 1, 1086–1087
  • Stem cell aging.
    Rudolph KL
    Mech Ageing Dev 2021, 193, 111394