Publikationen

2016

• Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation.
  Avila AI, Illing A, Becker F, Maerz LD, Morita Y, Philipp M, Burkhalter MD
  Nucleic Acids Res 2016, 44(13), 6252-61
  
• Gene Dosage Reductions of Trf1 and/or Tin2 Induce Telomere DNA Damage and Lymphoma Formation in Aging Mice.
  Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Fend L, Rudolph KL
  Leukemia 2016, 30(3), 749-53
  
• Telomere shortening leads to earlier age of onset in ALS mice.
  Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM
  Aging (Albany NY) 2016, 8(2), 382-93
  
• p21 shapes cancer evolution.
  Romanov VS, Rudolph KL
  Nat Cell Biol 2016, 18(7), 722-4
  
• Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.
  Scheffold A, Holtman IR, Dieni S, Brouwer N, Katz SF, Jebaraj BMC, Kahle PJ, Hengerer B, Lechel A, Stilgenbauer S, Boddeke EWGM, Eggen BJL, Rudolph KL, Biber K
  Acta Neuropathol Commun 2016, 4(1), 87
  
• Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.
  Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn** J, Tümpel** S, Rudolph** KL
  Nature 2016, 540(7633), 428-32 ** co-corresponding authors
  
• Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging.
  Tang D, Tao S, Chen Z, Koliesnik IO, Calmes PG, Hoerr V, Han B, Gebert N, Zörnig M, Löffler B, Morita** Y, Rudolph** KL
  J Exp Med 2016, 213(4), 535-53 ** co-corresponding authors
  
• Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding.
  Vranesic AC, Reiche J, Hoischen C, Wohlmann A, Bratsch J, Friedrich K, Günes B, Cappallo-Obermann H, Kirchhoff C, Diekmann S, Günes C, Huber O
  Hum Mol Genet 2016, 25(13), 2838-52
  
• SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling.
  Wang H, Diao D, Shi Z, Zhu X, Gao Y, Gao S, Liu X, Wu Y, Rudolph KL, Liu G, Li T, Ju Z
  Cell Stem Cell 2016, 18(4), 495-507
  
• Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing.
  Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL
  Nat Cell Biol 2016, 18(5), 480-90 recommended by "Faculty of 1000" - Prime