Publications

2024

• Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.
  Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, Kestler H, Englert C, Schaible R, Platzer M, Hoffmann S
  Genome Res 2024, 34(12), 2217-28
  
• Remodelling of the cardiac extracellular matrix proteome during chronological and pathological ageing.
  Santinha D, Vilaça A, Estronca L, Schüler SC, Bartoli C, De Sandre-Giovannoli A, Figueiredo A, Quaas M, Pompe T, Ori** A, Ferreira** L
  Mol Cell Proteomics 2024, 23(1), 100706 ** co-corresponding authors
  
• Circadian clock disruption engages the DREAM complex in suppressing cellular health
  Santos Valentim I, Javier Romero-Expósito F, Schwab K, Bayar M, Riege K, Fischer M, Olmedo M, Hoffmann S, A.Ermolaeva M
  bioRxiv 2024, https://doi.org/10.1101/2024.06.
  
• Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment.
  Schmidt D, Endres C, Hoefflin R, Andrieux G, Zwick M, Karantzelis N, Staehle HF, Vinnakota JM, Duquesne S, Mozaffari Jovein M, Pfeifer D, Becker H, Blazar BR, Zähringer A, Duyster J, Brummer T, Boerries M, Baumeister J, Shoumariyeh K, Li J, Green AR, Heidel FH, Tirosh I, Pahl HL, Leimkühler N, Köhler N, de Toledo MAS, Koschmieder S, Zeiser R
  Cancer Res 2024, 84(18), 2985-3003
  
• Consequences of GMPPB deficiency for neuromuscular development and maintenance.
  Schurig MK, Umeh O, Henze* H, Jung* MJ, Gresing L, Blanchard V, von Maltzahn J, Hübner* CA, Franzka* P
  Front Mol Neurosci 2024, 17, 1356326 * equal contribution
  
• p53 target ANKRA2 cooperates with RFX7 to regulate tumor suppressor genes.
  Schwab K, Riege K, Coronel L, Stanko C, Förste S, Hoffmann** S, Fischer** M
  Cell Death Discov 2024, 10(1), 376 ** co-corresponding authors
  
• Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
  Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME
  Sci Transl Med 2024, 16(734), eadg7162
  
• Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans.
  Sharifi* S, Chaudhari* P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff** H, Ermolaeva** M
  Nat Commun 2024, 15(1), 1702 * equal contribution, ** co-corresponding authors
  
• Fe-S cluster biosynthesis in chromatin protects genome stability and promotes DNA replication
  Shi R
  Dissertation 2024, Jena, Germany
  
• Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer's disease stages.
  Siano G, Varisco M, Terrigno M, Wang C, Scarlatti A, Iannone V, Groth M, Galas MC, Hoozemans JJM, Cellerino A, Cattaneo A, Di Primio C
  Front Cell Dev Biol 2024, 12, 1459573