Publications

2017

• Spindle Misorientation of Cerebral and Cerebellar Progenitors Is a Mechanistic Cause of Megalencephaly.
  Li H, Kroll T, Moll J, Frappart L, Herrlich P, Heuer H, Ploubidou A
  Stem Cell Reports 2017, 9(4), 1071-80
  

2016

• Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma.
  Li H, Frappart* L, Moll* J, Winkler* A, Kroll T, Hamann J, Kufferath I, Groth M, Taudien S, Schütte M, Yaspo ML, Heuer H, Lange BMH, Platzer M, Zatloukal K, Herrlich P, Ploubidou A
  Cancer Res 2016, 76(21), 6382-95 * equal contribution
  
• Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.
  Parra* LM, Hartmann* M, Schubach S, Ma J, Herrlich** P, Herrlich** A
  Sci Rep 2016, 6, 37464 * equal contribution, ** co-senior authors
  

2015

• Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 [CD44] and of Neuregulin-1 requires Substrate Dimerization.
  Hartmann M, Parra LM, Ruschel A, Lindner C, Morrison H, Herrlich** A, Herrlich** P
  J Biol Chem 2015, 290(28), 17041-54 ** co-senior authors, 2015 Best of jbc Papers of the Week Winner
  
• Tumor suppressor NF2 blocks cellular migration by inhibiting ectodomain cleavage of CD44.
  Hartmann* M, Parra* LM, Ruschel A, Schubert S, Li Y, Morrison H, Herrlich** A, Herrlich** P
  Mol Cancer Res 2015, 13(5), 879-90 * equal contribution, ** co-senior authors
  
• RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility.
  Li H, Moll J, Winkler A, Frappart L, Brunet S, Hamann J, Kroll T, Verlhac MH, Heuer H, Herrlich P, Ploubidou A
  Biol Open 2015, 4(4), 562-71
  
• Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44
  Parra* LM, Hartmann* M, Schubach S, Li Y, Herrlich P, Herrlich A
  Mol Cell Biol 2015, 35(19), 3381-95 * equal contribution
  
• The co-receptor function of CD44v6 and the effect of conditional deletion of CD44 isoforms on wound healing
  Ruschel A
  Dissertation 2015, Jena, Germany
  

2014

• The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters.
  Diefenbacher* ME, Reich* D, Dahley O, Kemler D, Litfin M, Herrlich P, Kassel O
  PLoS One 2014, 9(5), e97549 * equal contribution
  
• CD44 controls gene expression levels via two independent molecular actions
  Lindner C
  Dissertation 2014, Jena, Germany