Project Biochemistry (until 2023)

Publications

Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.
Obermeier K, Sachsenweger J, Friedl TWP, Pospiech H, Winqvist R, Wiesmüller L
Oncogene 2016, 35(29), 3796-806
TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress.
Pai GM, Zielinski A, Koalick D, Ludwig K, Wang ZQ, Borgmann K, Pospiech H, Rubio I
Oncotarget 2016, 7(51), 85365-80
Assembly of the Cdc45-Mcm2-7-GINS Complex, the Replication Helicase
Pospiech H, Szambowska A
In: The Initiation of DNA Replication in Eukaryotes (edited by Daniel Kaplan) 2016, 393-409, Springer International

The CENP-T C-Terminus Is Exclusively Proximal to H3.1 and not to H3.2 or H3.3.
Abendroth C, Hofmeister A, Hake SB, Kamweru PK, Miess E, Dornblut C, Küffner I, Deng W, Leonhardt H, Orthaus S, Hoischen C, Diekmann S
Int J Mol Sci 2015, 16(3), 5839-63
Elevated copper ion levels as potential cause of impaired kinesin-dependent transport processes.
Böhm KJ
Arch Toxicol 2015, 89(4), 565-72