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The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
Liu* X, Schneble-Löhnert* N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jörß T, Ori A, Godmann M, Wang ZQ
Cell Death Dis 2021, 12(2), 143 * equal contribution
Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling.
Lu J, Krepelova A, Rasa SMM, Annunziata F, Husak O, Adam L, Nunna S, Neri F
Sci Rep 2021, 11(1), 16668
Post-Translational Modification of MRE11: Its Implication in DDR and Diseases.
Lu R, Zhang H, Jiang YN, Wang ZQ, Sun L, Zhou ZW
Genes (Basel) 2021, 12(8)
An integrative understanding of the large metabolic shifts induced by antibiotics in critical illness.
Marfil-Sánchez A, Zhang L, Alonso-Pernas P, Mirhakkak M, Mueller M, Seelbinder B, Ni Y, Santhanam R, Busch A, Beemelmanns C, Ermolaeva** M, Bauer** M, Panagiotou** G
Gut Microbes 2021, 13(1), 1993598 ** co-corresponding authors
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load.
Marks D, Heinen N, Bachmann L, Meermeyer S, Werner M, Gallego L, Hemmerich P, Bader V, Winklhofer KF, Schröder E, Knauer SK, Müller T
Acta Neuropathol Commun 2021, 9(1), 66
Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing's sarcoma cells
Marx C, Schaarschmidt MU, Kirkpatrick J, Marx-Blümel L, Halilovic M, Westermann M, Hoelzer D, Meyer FB, Geng Y, Buder K, Schadwinkel HM, Siniuk K, Becker S, Thierbach R, Beck JF, Sonnemann* J, Wang* ZQ
Cell Biosci 2021, 11(1), 57 * equal contribution
Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.
Marx C, Sonnemann J, Beyer M, Maddocks ODK, Lilla S, Hauzenberger I, Piée-Staffa A, Siniuk K, Nunna S, Marx-Blümel L, Westermann M, Wagner T, Meyer FB, Thierbach R, Mullins CS, Kdimati S, Linnebacher M, Neri F, Heinzel T, Wang ZQ, Krämer OH
MOL ONCOL 2021, 15(12), 3404-29
Molecular characterization of hematopoietic stem cells after in vitro amplification on biomimetic 3D PDMS cell culture scaffolds.
Marx-Blümel* L, Marx* C, Sonnemann J, Weise F, Hampl J, Frey J, Rothenburger L, Cirri E, Rahnis N, Koch P, Groth M, Schober A, Wang ZQ, Beck JF
Sci Rep 2021, 11(1), 21163 * equal contribution
Implementing FAIR data management within the German Network for Bioinformatics Infrastructure (de.NBI) exemplified by selected use cases.
Mayer* G, Müller* W, Schork K, Uszkoreit J, Weidemann A, Wittig U, Rey M, Quast C, Felden J, Glöckner FO, Lange M, Arend D, Beier S, Junker A, Scholz U, Schüler D, Kestler HA, Wibberg D, Pühler A, Twardziok S, Eils J, Eils R, Hoffmann S, Eisenacher M, Turewicz M
Brief Bioinform 2021, 22(5) * equal contribution
A Novel Splice Variant of the Inhibitor of Growth 3 Lacks the Plant Homeodomain and Regulates Epithelial-Mesenchymal Transition in Prostate Cancer Cells.
Melekhova A, Leeder M, Pungsrinont T, Schmäche T, Kallenbach J, Ehsani M, Mirzakhani K, Rasa SMM, Neri F, Baniahmad A
Biomolecules 2021, 11(8), 1152