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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME
Sci Transl Med 2024, 16(734), eadg7162
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans.
Sharifi* S, Chaudhari* P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff** H, Ermolaeva** M
Nat Commun 2024, 15(1), 1702 * equal contribution, ** co-corresponding authors
Fe-S cluster biosynthesis in chromatin protects genome stability and promotes DNA replication
Shi R
Dissertation 2024, Jena, Germany
Endothelial LATS2 is a suppressor of bone marrow fibrosis
Sivaraj KK, Majev PG, Dharmalingam B, Schröder S, Banjanin B, Stehling M, Zeuschner D, Nordheim A, Schneider RK, Adams RH
Nat Cardiovasc Res 2024, 3(8), 951-69
Leiomodin 1 promotes myogenic differentiation by modulating Sirtuin 1
Späth* E, C.Schüler* S, Heinze I, Dau T, Minetti A, Hofmann M, von Maltzahn** J, Ori** A
bioRxiv 2024, https://doi.org/10.1101/2024.03. * equal contribution, ** co-corresponding authors
Npbwr1 signaling mediates fast antidepressant action.
Stein G, Aly JS, Lange L, Manzolillo A, Riege K, Brancato A, Hübner CA, Turecki G, Hoffmann S, Engmann O
Mol Psychiatry 2024 (epub ahead of print)
Transthyretin orchestrates vitamin B12-induced stress resilience.
Stein G, Aly JS, Manzolillo A, Lange L, Riege K, Hussain I, Heller EA, Cubillos S, Ernst T, Hübner CA, Turecki G, Hoffmann S, Engmann O
Biol Psychiatry 2024 (epub ahead of print)
Npbwr1 signaling mediates fast antidepressant action
Stein G, S.Aly J, Lange L, Manzolillo A, Riege K, Brancato A, A.Hübner C, Turecki G, Hoffmann S, Engmann O
bioRxiv 2024, 10.1101/2024.02.02.578166
Proteomic profiling reveals CEACAM6 function in driving gallbladder cancer aggressiveness through integrin receptor, PRKCD and AKT/ERK signaling.
Sugiyanto RN, Metzger C, Inal A, Truckenmueller F, Gür K, Eiteneuer E, Huth T, Fraas A, Heinze I, Kirkpatrick J, Sticht C, Albrecht T, Goeppert B, Poth T, Pusch S, Mehrabi A, Schirmacher P, Ji J, Ori A, Roessler S
Cell Death Dis 2024, 15(10), 780
An artificial intelligence-assisted clinical framework to facilitate diagnostics and translational discovery in hematologic neoplasia.
Tang M, Antić Ž, Fardzadeh P, Pietzsch S, Schröder C, Eberhardt A, van Bömmel A, Escherich G, Hofmann W, Horstmann MA, Illig T, McCrary JM, Lentes J, Metzler M, Nejdl W, Schlegelberger B, Schrappe M, Zimmermann M, Miarka-Walczyk K, Patsorczak A, Cario G, Renard BY, Stanulla M, Bergmann AK
EBioMedicine 2024, 104, 105171