Publications at FLI

2024

• Nonlinear DNA methylation trajectories in aging male mice.
  Olecka* M, van Bömmel* A, Best L, Haase M, Foerste S, Riege K, Dost T, Flor S, Witte OW, Franzenburg S, Groth M, von Eyss B, Kaleta C, Frahm C, Hoffmann S
  Nat Commun 2024, 15(1), 3074 * equal contribution
  
• The Greenland shark (Somniosus microcephalus) genome provides insights into extreme longevity
  Sahm A, Cherkasov* A, Liu* H, Voronov D, Siniuk K, Schwarz R, Ohlenschlaeger O, Foerste S, Bens M, Groth M, Goerlich I, Paturej S, Klages S, Braendl B, Olsen J, Bushnell P, Bech Poulsen A, Ferrando S, Garibaldi F, Lorenzo Drago D, Terzibasi Tozzini E, Mueller FJ, Fischer M, Kretzmer H, Domenici** P, Fleng Steffensen** J, Cellerino** A, Hoffmann** S
  bioRxiv 2024, 10.1101/2024.09.09.611499 * equal contribution, ** co-corresponding authors
  
• Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.
  Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, Kestler H, Englert C, Schaible R, Platzer M, Hoffmann S
  Genome Res 2024, 34(12), 2217-28
  
• Circadian clock disruption engages the DREAM complex in suppressing cellular health
  Santos Valentim I, Javier Romero-Expósito F, Schwab K, Bayar M, Riege K, Fischer M, Olmedo M, Hoffmann S, A.Ermolaeva M
  bioRxiv 2024, https://doi.org/10.1101/2024.06.
  
• p53 target ANKRA2 cooperates with RFX7 to regulate tumor suppressor genes.
  Schwab K, Riege K, Coronel L, Stanko C, Förste S, Hoffmann** S, Fischer** M
  Cell Death Discov 2024, 10(1), 376 ** co-corresponding authors
  
• Npbwr1 signaling mediates fast antidepressant action.
  Stein G, Aly JS, Lange L, Manzolillo A, Riege K, Brancato A, Hübner CA, Turecki G, Hoffmann S, Engmann O
  Mol Psychiatry 2024 (epub ahead of print)
  
• Transthyretin orchestrates vitamin B12-induced stress resilience.
  Stein G, Aly JS, Manzolillo A, Lange L, Riege K, Hussain I, Heller EA, Cubillos S, Ernst T, Hübner CA, Turecki G, Hoffmann S, Engmann O
  Biol Psychiatry 2024 (epub ahead of print)
  
• Npbwr1 signaling mediates fast antidepressant action
  Stein G, S.Aly J, Lange L, Manzolillo A, Riege K, Brancato A, A.Hübner C, Turecki G, Hoffmann S, Engmann O
  bioRxiv 2024, 10.1101/2024.02.02.578166
  
• An artificial intelligence-assisted clinical framework to facilitate diagnostics and translational discovery in hematologic neoplasia.
  Tang M, Antić Ž, Fardzadeh P, Pietzsch S, Schröder C, Eberhardt A, van Bömmel A, Escherich G, Hofmann W, Horstmann MA, Illig T, McCrary JM, Lentes J, Metzler M, Nejdl W, Schlegelberger B, Schrappe M, Zimmermann M, Miarka-Walczyk K, Patsorczak A, Cario G, Renard BY, Stanulla M, Bergmann AK
  EBioMedicine 2024, 104, 105171
  

2023

• Recurrent DNMT3B rearrangements are associated with unfavorable outcome in dicentric (9;20)-positive pediatric BCP-ALL.
  Antić Ž, van Bömmel A, Riege K, Lentes J, Schröder C, Alten J, Eckert C, Fuhrmann L, Steinemann D, Lenk L, Schewe DM, Zimmermann M, Schrappe M, Schlegelberger B, Cario G, Hoffmann S, Bergmann AK
  Leukemia 2023, 37(12), 2522-5