Rudolph Research Group

Publications

2018

  • Cohesin deficiency enhances hematopoietic stem cell self-renewal in the context of aging and inflammation by impairing NK-ƙB induced differentiation.
    Chen Z
    Dissertation 2018, Jena, Germany
  • Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan.
    Diao D, Wang H, Li T, Shi Z, Jin X, Sperka T, Zhu X, Zhang M, Yang F, Cong Y, Shen L, Zhan Q, Yan J, Song Z, Ju Z
    EMBO Rep 2018, 19(10), e45494
  • Cellular and epigenetic drivers of stem cell ageing.
    Ermolaeva** M, Neri** F, Ori** A, Rudolph** KL
    Nat Rev Mol Cell Biol 2018, 19(9), 594-610 ** co-corresponding authors
  • Telomeres in cancer.
    Gunes C, Avila AI, Rudolph KL
    Differentiation 2018, 99, 41-50
  • RelB regulates Th17 differentiation in a cell-intrinsic manner.
    Koliesnik IO, Andreas N, Romanov VS, Sreekantapuram S, Krljanac B, Haenold R, Weih F
    Immunobiology 2018, 223(2), 191-9
  • A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.
    Siegle* L, Schwab* JD, Kühlwein* SD, Lausser L, Tümpel S, Pfister AS, Kühl** M, Kestler** HA
    PLoS One 2018, 13(3), e0195126 * equal contribution, ** co-senior authors
  • Senescence mirrors the extent of liver fibrosis in chronic hepatitis C virus infection.
    Wandrer F, Han B, Liebig S, Schlue J, Manns MP, Schulze-Osthoff K, Bantel H
    Aliment Pharmacol Ther 2018, 48(3), 270-80

2017

  • Identification of novel Hox target genes with essential roles in hematopoietic stem cell self-renewal and differentiation
    Baig AH
    Dissertation 2017, Jena, Germany
  • Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice.
    Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Martinez L, Rudolph KL
    Leukemia 2017, 31(12), 2853 Erratum for Leukemia 2016 volume 30 page 749
  • Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
    Meena JK, Cerutti A, Beichler C, Morita Y, Bruhn C, Kumar M, Kraus JM, Speicher MR, Wang ZQ, Kestler HA, Fagagna Fdd, Günes C, Rudolph KL
    EMBO J 2017, 36(19), 2922-4 Erratum for EMBO J 2015 volume 34 page 1371