Publications

2017

• The use of urinary proteomics in the assessment of suitability of mouse models for ageing.
  Nkuipou-Kenfack E, Schanstra JP, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands JL, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber TB, Rudolph KL, Pich A, Mischak H, Zürbig P
  PLoS One 2017, 12(2), e0166875
  
• Hoxa9 activation by epigenetic alterations in aging muscle stem cells induces developmental signals impairing regeneration of aging muscle
  Schwörer S
  Dissertation 2017, Jena, Germany
  
• Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.
  Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler HA, Kühl M, Rudolph KL
  EMBO J 2017, 36(19), 2920-1 Erratum for EMBO J 2015 volume 34 page 624
  
• Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice.
  Zhu X, Shen W, Wang Y, Jaiswal A, Ju Z, Sheng Q
  Signal Transduct Target Ther 2017, 2, 17017
  

2016

• Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation.
  Avila AI, Illing A, Becker F, Maerz LD, Morita Y, Philipp M, Burkhalter MD
  Nucleic Acids Res 2016, 44(13), 6252-61
  
• Gene Dosage Reductions of Trf1 and/or Tin2 Induce Telomere DNA Damage and Lymphoma Formation in Aging Mice.
  Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Fend L, Rudolph KL
  Leukemia 2016, 30(3), 749-53
  
• Telomere shortening leads to earlier age of onset in ALS mice.
  Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM
  Aging (Albany NY) 2016, 8(2), 382-93
  
• p21 shapes cancer evolution.
  Romanov VS, Rudolph KL
  Nat Cell Biol 2016, 18(7), 722-4
  
• Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.
  Scheffold A, Holtman IR, Dieni S, Brouwer N, Katz SF, Jebaraj BMC, Kahle PJ, Hengerer B, Lechel A, Stilgenbauer S, Boddeke EWGM, Eggen BJL, Rudolph KL, Biber K
  Acta Neuropathol Commun 2016, 4(1), 87
  
• Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.
  Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn** J, Tümpel** S, Rudolph** KL
  Nature 2016, 540(7633), 428-32 ** co-corresponding authors