Publications

2022

• Vitamin A metabolism in niche cells activates retinoic acid signaling and impairs stem cell function and skeletal muscle maintenance in aging mice
  Becker F
  Dissertation 2022, Jena
  
• Meeting Report: Aging Research and Drug Discovery
  Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald Collin Y, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Borch Jensen M, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M
  Aging (Albany NY) 2022, 14(2), 530–543
  
• Characterization of Novel α-Mangostin and Paeonol Derivatives With Cancer-Selective Cytotoxicity.
  Nunna S, Huang YP, Rasa M, Krepelova A, Annunziata F, Adam L, Käppel S, Hsu MH, Neri F
  Mol Cancer Ther 2022, 21(2), 257-70
  
• Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.
  Rasa* SMM, Annunziata* F, Krepelova A, Nunna S, Omrani O, Gebert N, Adam L, Käppel S, Höhn S, Donati G, Jurkowski TP, Rudolph KL, Ori A, Neri F
  Cell Rep 2022, 39(13), 111017 * equal contribution
  
• Association of Telomere Length With Risk of Disease and Mortality.
  Schneider CV, Schneider KM, Teumer A, Rudolph KL, Hartmann D, Rader DJ, Strnad P
  JAMA INTERN MED 2022, 182(3), 291-300
  
• pH-sensitive packaging of cationic particles by an anionic block copolymer shell.
  Solomun JI, Martin L, Mapfumo P, Moek E, Amro E, Becker F, Tuempel S, Hoeppener S, Rudolph KL, Traeger A
  J Nanobiotechnology 2022, 20(1), 336
  
• Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.
  Suo M, Rommelfanger MK, Chen Y, Amro EM, Han B, Chen Z, Szafranski K, Chakkarappan SR, Boehm BO, MacLean AL, Rudolph KL
  Blood 2022, 139(17), 2653-65
  
• PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
  Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A
  Nat Commun 2022, 13(1), 2982
  
• Identification of dynamic driver sets controlling phenotypical landscapes.
  Werle SD, Ikonomi N, Schwab JD, Kraus JM, Weidner FM, Rudolph KL, Pfister AS, Schuler R, Kühl M, Kestler HA
  Comput Struct Biotechnol J 2022, 20, 1603-17
  
• S-nitrosoglutathione reductase (GSNOR) deficiency impairs hematopoietic stem cell proteostasis
  Yi W
  Dissertation 2022, Jena, Germany