Publications

2021

• Poly(ADP-ribose) regulation in cell cycle control and cancer therapy
  Siniuk K
  Dissertation 2021, Jena, Germany
  
• HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
  Tapias* A, Lázaro* D, Yin* BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ
  Elife 2021, 10, e61531 * equal contribution
  
• Beyond HAT Adaptor: TRRAP Liaisons with Sp1-Mediated Transcription.
  Yin BK, Wang ZQ
  Int J Mol Sci 2021, 22(22)
  

2020

• Bi-allelic HPDL Variants Cause a Neurodegenerative Disease Ranging from Neonatal Encephalopathy to Adolescent-Onset Spastic Paraplegia.
  Husain RA, Grimmel M, Wagner M, Hennings JC, Marx C, Feichtinger RG, Saadi A, Rostásy K, Radelfahr F, Bevot A, Döbler-Neumann M, Hartmann H, Colleaux L, Cordts I, Kobeleva X, Darvish H, Bakhtiari S, Kruer MC, Besse A, Ng ACH, Chiang D, Bolduc F, Tafakhori A, Mane S, Ghasemi Firouzabadi S, Huebner AK, Buchert R, Beck-Woedl S, Müller AJ, Laugwitz L, Nägele T, Wang ZQ, Strom TM, Sturm M, Meitinger T, Klockgether T, Riess O, Klopstock T, Brandl U, Hübner CA, Deschauer M, Mayr JA, Bonnen PE, Krägeloh-Mann I, Wortmann SB, Haack TB
  Am J Hum Genet 2020, 107(2), 364-73
  
• Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.
  Journiac N, Gilabert-Juan J, Cipriani S, Benit P, Liu X, Jacquier S, Faivre V, Delahaye-Duriez A, Csaba Z, Hourcade T, Melinte E, Lebon S, Violle-Poirsier C, Oury JF, Adle-Biassette H, Wang ZQ, Mani S, Rustin P, Gressens P, Nardelli J
  Cell Rep 2020, 31(2), 107506
  
• ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration.
  Kidiyoor GR, Li Q, Bastianello G, Bruhn C, Giovannetti I, Mohamood A, Beznoussenko GV, Mironov A, Raab M, Piel M, Restuccia U, Matafora V, Bachi A, Barozzi S, Parazzoli D, Frittoli E, Palamidessi A, Panciera T, Piccolo S, Scita G, Maiuri P, Havas KM, Zhou ZW, Kumar A, Bartek J, Wang ZQ, Foiani M
  Nat Commun 2020, 11(1), 4828
  
• Biomimetic reconstruction of the hematopoietic stem cell niche for in vitro amplification of human hematopoietic stem cells.
  Marx-Blümel L, Marx C, Weise F, Frey J, Perner B, Schlingloff G, Lindig N, Hampl J, Sonnemann J, Brauer D, Voigt A, Singh S, Beck B, Jäger UM, Wang ZQ, Beck JF, Schober A
  PLoS One 2020, 15(6), e0234638
  
• Growth inhibitory role of the p53 activator SCH 529074 in non‑small cell lung cancer cells expressing mutant p53.
  Nenkov M, Ma Y, Haase D, Zhou Z, Li Y, Petersen I, Lu G, Chen Y
  Oncol Rep 2020, 43(2), 2073-82
  
• NBS1 interacts with Notch signaling in neuronal homeostasis.
  Zhou ZW, Kirtay M, Schneble N, Yakoub G, Ding M, Rüdiger T, Siniuk K, Lu R, Jiang YN, Li TL, Kaether C, Barzilai A, Wang ZQ
  Nucleic Acids Res 2020, 48(19), 10924-39
  

2019

• C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7 /LIN28B circuit in mice.
  Ackermann T, Hartleben* G, Müller* C, Mastrobuoni G, Groth M, Sterken BA, Zaini MA, Youssef SA, Zuidhof HR, Krauss SR, Kortman G, de Haan G, de Bruin A, Wang ZQ, Platzer M, Kempa S, Calkhoven CF
  Commun Biol 2019, 2, 208 * equal contribution